Engineered nanopores for bioanalytical applications / Joshua B. Edel, Tim Albrecht.

This book is the first to explore both the development and application of nanopores with practical analytical applications as the primary focus. These nanoscale analytical techniques have exciting potential as they can be used in applications such as DNA sequencing, DNA fragment sizing, DNA/protein binding, and protein/protein binding. Importantly this book aims to provide a solid professional reference on nanopores for readers in both academia and industry, and engineering and biomedical fields. In addition, the aim of this book is to share with the scientific and engineering communities the experimental and fabrication methods necessary to carry out nanopore-based experiments for developing new devices. Includes application case studies for detection, identification and analysis of biomolecules and related functional nanomaterials Introduces the techniques of manufacturing solid state materials with functional nanopores Explains the use of nanopores in DNA sequencing and the wider range of applications from environmental monitoring to forensics.

Print version record.

Includes bibliographical references and index.

Chapter 1. Ion transport in nanopores / T. Albrecht, T. Gibb and P. Nuttall -- chapter 2. DNA translocation / Oliver Otto and Ulrich F. Keyser -- chapter 3. Instrumentation for low-noise high-bandwidth nanopore recording / Vincent Tabard-Cossa -- chapter 4. Biological pores on lipid bilayers / Joseph W.F. Robertson -- chapter 5. Solid-state nanopore fabrication / Thomas Gibb and Mariam Ayub -- chapter 6. Case studies using solid-state pores / Gaurav Goyal [and three others].